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# Macronutrients
- We need a larger amount
- Provides Calories
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## Carbohydrates
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- Provides 4 calories per gram
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- The storage form of carbohydrates in the body is as glycogen (very branched sugar). Stored in muscles and in liver
- Only **monosaccharides** can be directly absorbed. Everything else must be broken down first.
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### Simple
- Mono/Disaccharides
Monosaccharides include:
- Glucose
- Fructose (fruit sugar)
- Galactose
Disaccharides include:
- Sucrose (glucose + fructose)
- Maltose (glucose + glucose)
- Lactose (glucose + galactose)
### Complex
- Polysaccharides
Polysaccharides include:
- Starches
- Amalose
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- Amalopectin (More branched)
- Fiber
- Photosynthesis +Sun + carbon + hydrogen + oxygen
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## Protein
- Provides 4 calories per gram
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- Protein is composed of amino acids
- There are **9 essential** amino acids
- There are **11 non-essential** amino acids
- Donkey bridge: If it starts with the letter A, it's a non-essential amino acid
- Protein has nitrogen alongside hydrogen, carbon, and
- To use protein as energy, it must be **deanimated** .
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## Lipids/Fats
- Provides 9 calories per gram
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- Fat is composed of hydrocarbon chains
- Tryglicerine - 3 fatty acid chains, with glycerol backbone
### Saturated Fats
- Saturated fats have no double bonds
### Unsaturated Fats
- Unsaturated fats have one or more double bond
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### HDL (High Density Lipoprotein)
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- We want high HDL levels
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- Takes cholesterol out of the cells to the liver to be excreted
### LDL (Low Density Lipoprotein)
- We want low LDL levels
- Takes cholesterol into arteries
### oLDL (Oxidized Low Density Lipoprotein)
- Damaged LDL
- Deposits plaque
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# Micronutrients
- Smaller Amounts
- Don't provide calories
## Vitamins
## Minerals
## Water
- Not a macro or micronutrient, but still one of the 6 major nutrition groups
## Alcohol
- While not in a food group, provides 7 calories per gram
# Digestive System
1. Mouth
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- Digestion of carbs/starches, and fats begin here.
- Mechanical digestion (chewing)
- Chemical digestion (amalayses (starch) and lipases (fat) in the mouth)
2. Esophagus
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- Peristalsis is an involuntary relaxation and contraction of muscles to move food down
1. Gastroesophageal/Lower Esophageal/Cardiac Sphincter
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- When this sphincter misfires, it can cause heartburn or gastroesphageal reflex disease (GERD)
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2. Stomach
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- Protein
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3. Pyloric Sphincter
4. Small Intestine (DJI)
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1. Duodenum
2. Jejunum
3. Ilium
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5. Ilieocecal Valve
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# DRI (Dietary Reference Intakes)
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## EAR (Estimated Average Requirement)
- Meet the requirements of 50% of healthy individuals
## RDA (Recommended Daily Allowance)
- 97.5% of healthy people
- EAR plus a margin of safety
## AI (Adequate Intake)
- The average amount of nutrients a healthy population needs to consume
## UL (Upper Limit)
- Prevents overconsumption
## AMDR (Acceptable Macronutrient Distribution Range)
- Carbs: 45-65% / kCal
- Protein: 10-35% / kCal
- Fats: 20-35% / kCal
## EER (Estimated Energy Requirements)
- Average estimated caloric needs
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- Actual needs vary
# Hormones
## Insulin
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Insulin is made by the beta cells in the pancreas, and promotes absorption of glucose from the blood into liver, fat, and skeletal muscles.
- Insulin is released when blood sugar levels are too high
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## Glucagon
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Glucagon is a peptide hormone, produced by the alpha cells of the pancreas. It's the opposite of insulin, and it increases blood sugar levels.
- Glucagon is released when blood sugar levels are too low
## Ghrelin
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Ghrellin is known as the "hunger hormone", and it increases the drive to eat. It increases gastric motility and stimulates the secretion of gastric acid.
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## Leptin
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Leptin's primary role is to regulate long-term energy balance. High leptin levels indicate to the brain that energy reserves are high.
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# Study Types
## Exprimental
- A systematic way of testing a hypothesis
## Epidemiological
- Observations of the occurrence, distribution, and associations