Proteins are large, complex, organic molecules made up of **amino acids**. - Contain carbon, hydrogen, oxygen, and nitrogen - Found in plants, animals, bacteria, and viruses - Major functions of protein in the body: - To build new cells and many parts of cells - As a component in hardened structures like hair and nails - As enzymes to speed chemical reactions - As lubricants to ease movement - In clotting compounds in blood - To build antibodies that fight disease organisms - As compounds that help maintain fluid and pH balance - As transporters - To make certain hormones - As an energy source (as a last resort) # Introduction - By helping to maintain fluid balance, proteins prevent **edema** (accumulation of fluid in tissues - Proteins also help maintain **acid-base balance**. - Maintaining the proper pH of body fluids - Acts as a buffer # Amino acids - Amino acids are nitrogen containing chemical units that comprise proteins - There are 20 different amino acids found in the proteins of the human body - Each amino acid has a carbon atom that anchors - Hydrogen atom - Amino or nitrogen containing group - R group (side chain) - carboxylic acid group - nonessential amino acids are a group of amino acids that the body can make - Essential amino acids are amino acids the body cannot make or cannot make enough of to meet its needs - Conditionally essential amino acids are the amino acids the body cannot make or cannot make enough of to meet its needs - There are 9 essential acids and 11 non-essential acids | Essential | Nonessential | | ---------------------------- | ------------- | | Histidine | Alanine | | Isoleucine | Aspartic acid | | Leucine | Asparagine | | Lysine | Glutanic acid | | Methionine | Serine | | Phenylanaline | Argine | | Threonine | Cysteine | | Tryptophan (extra important) | GLutamine | | Valine | Glycine | | | Proline | | | Tyrosine | TT HILL MVP # Synthesis A specific order of amino acids is needed to formulate a protein. # DNA - DNA (deoxyribonucleic acid) provides instructions for making proteins. - **Genes** are a portion of DNA - To make proteins, cells assemble amino acids into specific sequences according to information from DNA - A **peptide bond** is a chemical attraction that connects two amino acids together -